Tetradrachm - Antiochos III Megas Antioch on the Orontes

Antiochos III earned the epithet "Megas" — the Great — largely through his ambitious Anabasis of 212–205 BC, a sweeping eastern campaign that temporarily restored Seleucid authority over Parthia and Bactria and drew deliberate comparison to Alexander. The Antioch mint was the empire's most prolific silver producer throughout his reign, and tetradrachms of this type circulated across a territory stretching from the Aegean coast to the Hindu Kush.

His catastrophic defeat by Rome at Magnesia in 190 BC forced the Treaty of Apamea the following year, stripping the empire of Asia Minor and imposing crippling indemnities — conditions that effectively ended any Seleucid pretension to Mediterranean power. SC 1042.1 places this die among the Antioch issues prior to that contraction.