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| Issuer | Magyar Nemzeti Bank (Hungarian National Bank) |
|---|---|
| Year | 2022 |
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| Currency | Forint (1946-date) |
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|---|---|
| Obverse script | Latin |
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| Reverse description | The reverse features a detailed scientific depiction of a nucleoside-modified mRNA lipid nanoparticle, rendered as a spherical fat particle rendered in cross-section to reveal the encapsulated modified mRNA helices within its interior. Adjacent to the central nanoparticle, enlarged representations of the mRNA helices are displayed for scientific clarity. The names of the pioneering researchers credited with the discovery — Ian MacLachlan, Norbert Pardi, Drew Weissman, and Katalin Karikó — are inscribed in the field alongside the descriptive legend identifying the depicted structure in Hungarian. |
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| Additional information |
Katalin Karikó spent decades at the University of Pennsylvania having her mRNA research defunded, demoted, and largely ignored by the American academic establishment. The Hungarian National Bank issued this coin the year before she shared the Nobel Prize in Physiology or Medicine with Drew Weissman — the 2023 award validating work that had been dismissed as a scientific dead end for most of the 1990s and 2000s. The critical breakthrough was modifying nucleosides in synthetic mRNA to prevent the immune system from destroying it before it could function.